ta3r friability tester  (Erweka Inc)

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: QTPP and CQAs of sildenafil MODTs.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: Summary of model fitting and statistical analysis.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: Linear correlation plot relating mean granule size, bulk density, angle of repose, crushing strength, friability, disintegration time, and drug release after 30 min between the predicted and the actual values.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: Measured response results of prepared ODMTs (mean ± SD).

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: ANOVA analysis of ODMTs measured responses.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: Response surface plots showing the influence of MCC (X 1 ) and PPGS (X 2 ) on measured MODTs responses; crushing strength (y 4 ), friability (y 5 ), disintegration time (y 6 ), and percent release after 30 min (y 7 ).

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: Lack-of-fit test of measured responses.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: The constraints adopted for developed design space.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques:

Journal: Pharmaceutics

Article Title: Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology

doi: 10.3390/pharmaceutics15030923

Figure Lengend Snippet: Predicted and experimental values of optimized run with their relative errors.

Article Snippet: Using a friability tester (Erweka, TA3R, Heusenstamm, Germany), about 6.5 g (M 1 ) of ODMTs were tumbled at 25 rpm for 4 min. After tumbling, the ODMTs were collected, de-dusted, and weighed once more (M 2 ).

Techniques: